Three people have been charged in connection to a death involving a 2-year-old child in St. Francois County. Learn more tonight at 6:00.
A Farmington, Missouri woman lost her life after her pickup crashed on a Missouri road late Friday night.
Three teens were injured - two with serious injuries - after two ATVs collided head on overnight near Oak Ridge.
According to the Missouri Highway Patrol, the Doniphan area is having trouble making some calls after a backhoe ran over a line.
Illinois' governor is promising tighter controls after a review found that the Illinois Medicaid program paid an estimated $12 million for medical services for people who were dead.
What a beautiful day! Bryan McCormick says cool tonight, and mild for Easter Sunday. Here is an updated list of Easter events around the Heartland.
Missouri Republicans have outlined a new gun proposal. Find out what's involved tonight at 6:04.
A jury has awarded $14 million to a suburban Chicago woman after she had a stroke due to taking a certain birth control medicine.
A western Kentucky man faces drug related charges after a traffic stop on Saturday morning.
Kentucky residents will get a chance to review state academic standards involving Common Core later this year.
Josh Frydman will have Blues-Blackhawks & Nats-Cardinals highlights along with SEMO softball in sports.
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Multiple crews were on the scene of a fire in Perry County, Missouri on Wednesday, August 23.
Bentley was born however with a Neuro Degenerative disease called PKAN, the symptoms can often be like Parkinson's disease. But a few months ago they found out about a possible cure.
A marathon in Cape Girardeau, Missouri will honor veterans and first responders. The Tunnel to Towers 5K Run and Walk is scheduled for Saturday, Sept. 9.
During the Great American Eclipse on Monday, August 21, weather balloons were released to travel near space.
An area economic development agency hopes to entice major auto makers to Western Kentucky. The move could bring thousands of jobs with it.
A 15-month-old girl has died after being left in an SUV that was in the Mason Procter and Gamble parking lot on Wednesday, according to Warren County Coroner Dr. Russell Uptegrove.